In this course, students will learn the remarkable phenomena occurring at lower dimensions which are universally applicable to a wide range of two- dimensional materials and their heterostructures. The course will provide the fundamental physics&chemistry knowledge required to understand the macroscopic behaviors two- dimensional materials starting from graphene and spanning a wide range of spectrum including graphyne, boron nitride, transition metal dichalcogenides, silicene, germanene, phosphorene, antimonene, nitrogene, metal hydroxides and polymers in two-dimensional networks. This course will also present important applications of two-dimensional materials in energy storage/harvesting, carbon capture and water filtering devices as well as discussing the quantum effects such as superconductivity, superlubricity and nano-capacitance that can be observed in low-dimensional materials. The course is research oriented and successful students will be able to contribute to research papers at the end of the course.