Tissue engineering combines the skills of engineering
and knowledge of principle biology to generate, restore
and replace damaged tissues and organs. To engineer
living tissues mimicking conditions in living organism is
essential. Therefore, tissue engineering is considered a
biomedical engineering discipline and a potential
alternative to tissue and organ transplantation. This
course is built on three main pillars of tissue engineering:
cells, scaffolds, and growth factors. Initially stem cells
and differentiation is discussed as well as cell-based
tissue engineering applications. Then design and
characterization of biomaterials and nanomaterials as
tissue scaffolds are covered. Here, various bio-
fabrication techniques including 3D bioprinting are
detailed. This course also covers the interaction with
biomaterial surface, mechanical loading, biologic
regulators, and culture conditions. Finally, examples of
tissue engineering-based procedures that can alleviate
specific diseases and clinical translation of regenerative
therapies are analyzed as case studies with student
presentations.
This course also contains a laboratory session. At this
session students will learn to handle mammalian cell
cultures, prepare hydrogel and polymer scaffolds,
perform tissue culture and characterization.
|