|
Tissue engineering combines the skills of engineering
and knowledge of principle biology to generate,
restore and replace damaged tissues and organs. To
engineer living tissues mimicking conditions in living
organism is essential. Therefore, tissue engineering is
considered a biomedical engineering discipline and a
potential alternative to tissue and organ
transplantation. This course is built on three main
pillars of tissue engineering: cells, scaffolds, and
growth factors. Initially stem cells and differentiation
is discussed as well as cell-based tissue engineering
applications. Then design and characterization of
biomaterials and nanomaterials as tissue scaffolds are
covered. Here, various bio-fabrication techniques
including 3D bioprinting are detailed. This course also
covers the interaction with biomaterial surface,
mechanical loading, biologic regulators, and culture
conditions. Finally, examples of tissue engineering-
based procedures that can alleviate specific diseases
and clinical translation of regenerative therapies are
analyzed as case studies with student presentations.
This course also contains a laboratory session. At this
session students will learn to handle mammalian cell
cultures, prepare hydrogel and polymer scaffolds,
perform tissue culture and characterization.
|
