Fundamentals of Nanoscience (NS 218)

2023 Spring
Faculty of Engineering and Natural Sciences
Natural Sciences(NS)
Canan At─▒lgan,
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Formal lecture,Interactive lecture
Interactive,Learner centered,Communicative,Discussion based learning,Guided discovery
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Physical principles operative in the 1-100 nm size range. Detailed study of the physics governing behavior of molecules or clusters of molecules at this scale. Inter and intramolecular interactions. Forces driving molecules to flow. Water as a solvent. Self-assembly of molecules.


Provide a physics-based understanding of the processes important for nanoengineering so that each student will develop the heuristics on how man-made nanostructures and biological nanomachines behave.


  • list the differences between the properties of nano- and macroscale materials.
  • calculate basic intermolecular interactions between atoms and/or particles and classify them as strong/weak based on a comparison with thermal energy
  • categorize forces as short- versus long-range based on the power dependence on separation.
  • relate time scale of motion of nanoparticles to their sizes using the diffusion equation.
  • identify nanomachines and classify them, e.g. as transport, catalyst, motor, etc.
  • calculate the charge distribution near nanoparticles with uniform surface charges.
  • describe the effect of salt on the behavior of nanoparticles
  • given the general interaction parameters of a mixture of molecules, identify if a self-assembly process will be observed and estimate the morphology of the final equilibrium structure.
  • explain hydrogen bonding and the driving forces that lead to hydrophobic behavior.
  • evaluate results obtained from experiments based-on forces operating at the nanoscale


1. Understand the world, their country, their society, as well as themselves and have awareness of ethical problems, social rights, values and responsibility to the self and to others. 1

2. Understand different disciplines from natural and social sciences to mathematics and art, and develop interdisciplinary approaches in thinking and practice. 2

3. Think critically, follow innovations and developments in science and technology, demonstrate personal and organizational entrepreneurship and engage in life-long learning in various subjects; have the ability to continue to educate him/herself. 4

4. Communicate effectively in Turkish and English by oral, written, graphical and technological means. 4

5. Take individual and team responsibility, function effectively and respectively as an individual and a member or a leader of a team; and have the skills to work effectively in multi-disciplinary teams. 2

1. Possess sufficient knowledge of mathematics, science and program-specific engineering topics; use theoretical and applied knowledge of these areas in complex engineering problems. 5

2. Identify, define, formulate and solve complex engineering problems; choose and apply suitable analysis and modeling methods for this purpose. 2

3. Develop, choose and use modern techniques and tools that are needed for analysis and solution of complex problems faced in engineering applications; possess knowledge of standards used in engineering applications; use information technologies effectively. 3

4. Have the ability to design a complex system, process, instrument or a product under realistic constraints and conditions, with the goal of fulfilling specified needs; apply modern design techniques for this purpose. 2

5. Design and conduct experiments, collect data, analyze and interpret the results to investigate complex engineering problems or program-specific research areas. 2

6. Possess knowledge of business practices such as project management, risk management and change management; awareness on innovation; knowledge of sustainable development. 1

7. Possess knowledge of impact of engineering solutions in a global, economic, environmental, health and societal context; knowledge of contemporary issues; awareness on legal outcomes of engineering solutions; knowledge of behavior according to ethical principles, understanding of professional and ethical responsibility. 2

8. Have the ability to write effective reports and comprehend written reports, prepare design and production reports, make effective presentations, and give and receive clear and intelligible instructions. 2

1. Use mathematics (including derivative and integral calculations, probability and statistics, differential equations, linear algebra, complex variables and discrete mathematics), basic sciences, computer and programming, and electronics engineering knowledge to (a) Design and analyze complex electronic circuits, instruments, software and electronics systems with hardware/software or (b) Design and analyze communication networks and systems, signal processing algorithms or software 2

1. Applying fundamental and advanced knowledge of natural sciences as well as engineering principles to develop and design new materials and establish the relation between internal structure and physical properties using experimental, computational and theoretical tools. 3

2. Merging the existing knowledge on physical properties, design limits and fabrication methods in materials selection for a particular application or to resolve material performance related problems. 2

3. Predicting and understanding the behavior of a material under use in a specific environment knowing the internal structure or vice versa. 2

1. Familiarity with concepts in statistics and optimization, knowledge in basic differential and integral calculus, linear algebra, differential equations, complex variables, multi-variable calculus, as well as physics and computer science, and ability to use this knowledge in modeling, design and analysis of complex dynamical systems containing hardware and software components. 2

2. Ability to work in design, implementation and integration of engineering applications, such as electronic, mechanical, electromechanical, control and computer systems that contain software and hardware components, including sensors, actuators and controllers. 2


  Percentage (%)
Final 50
Midterm 40
Participation 10



Dill, K.A., Bromberg, S., and Stigter, D., Molecular Driving Forces, Statistical Thermodynamics in Biology. Garland Science, Taylor & Francis Group, 2002. QC311.5 .D55 2002.


Introduction to Nanoscience, S. M. Lindsay, Oxford.
Intermolecular and Surface Forces (2nd edition), J. Israelachvili, Academic Press.