Cell Biology (BIO 332)

2023 Spring
Faculty of Engineering and Natural Sciences
6/7 ECTS (for students admitted in the 2013-14 Academic Year or following years)
Emine Süphan Bakkal suphanbakkal@sabanciuniv.edu,
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Formal lecture,Interactive lecture,Workshop,Laboratory
Interactive,Learner centered,Communicative,Discussion based learning
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The fundamental molecular processes of cells are examined using evidence from biochemical, physiological and microscopic analyses. Topics include: the logical spatial and temporal organization and regulation of of metabolism; generation and function of cellular compartments; the organization and regulation of cell growth and division; and cell-environment and cell-cell interactions. Comparisons among prokaryotic , free-living eukaryotic and metazoan eukaryotic cells of diverse organisms are used to assess the universality of these processes and their mechanisms.


Teaching basic cell biology at molecular and systemic levels.


  • Know basic principles governing organization, interaction and function of cellular components.
  • Understand regulation of metabolic and genetic activities in cells.
  • Understand the molecular mechanisms involved in signaling within and outside the cell.
  • Understand how activities of different types of cells are regulated in a complementary fashion in higher organisms.
  • Be able to develop models for higher organizational states of cells.
  • Have sufficient laboratory skills to identify basic cellular components under the microscope and to be able perform basic cellular activity measurements.


1. Understand the world, their country, their society, as well as themselves and have awareness of ethical problems, social rights, values and responsibility to the self and to others. 5

2. Understand different disciplines from natural and social sciences to mathematics and art, and develop interdisciplinary approaches in thinking and practice. 4

3. Think critically, follow innovations and developments in science and technology, demonstrate personal and organizational entrepreneurship and engage in life-long learning in various subjects; have the ability to continue to educate him/herself. 4

4. Communicate effectively in Turkish and English by oral, written, graphical and technological means. 5

5. Take individual and team responsibility, function effectively and respectively as an individual and a member or a leader of a team; and have the skills to work effectively in multi-disciplinary teams. 5

1. Possess sufficient knowledge of mathematics, science and program-specific engineering topics; use theoretical and applied knowledge of these areas in complex engineering problems. 4

2. Identify, define, formulate and solve complex engineering problems; choose and apply suitable analysis and modeling methods for this purpose. 4

3. Develop, choose and use modern techniques and tools that are needed for analysis and solution of complex problems faced in engineering applications; possess knowledge of standards used in engineering applications; use information technologies effectively. 4

4. Have the ability to design a complex system, process, instrument or a product under realistic constraints and conditions, with the goal of fulfilling specified needs; apply modern design techniques for this purpose. 2

5. Design and conduct experiments, collect data, analyze and interpret the results to investigate complex engineering problems or program-specific research areas. 4

6. Possess knowledge of business practices such as project management, risk management and change management; awareness on innovation; knowledge of sustainable development. 2

7. Possess knowledge of impact of engineering solutions in a global, economic, environmental, health and societal context; knowledge of contemporary issues; awareness on legal outcomes of engineering solutions; knowledge of behavior according to ethical principles, understanding of professional and ethical responsibility. 3

8. Have the ability to write effective reports and comprehend written reports, prepare design and production reports, make effective presentations, and give and receive clear and intelligible instructions. 2

1. Comprehend key concepts in biology and physiology, with emphasis on molecular genetics, biochemistry and molecular and cell biology as well as advanced mathematics and statistics. 5

2. Develop conceptual background for interfacing of biology with engineering for a professional awareness of contemporary biological research questions and the experimental and theoretical methods used to address them. 5

1. Use mathematics (including derivative and integral calculations, probability and statistics, differential equations, linear algebra, complex variables and discrete mathematics), basic sciences, computer and programming, and electronics engineering knowledge to (a) Design and analyze complex electronic circuits, instruments, software and electronics systems with hardware/software or (b) Design and analyze communication networks and systems, signal processing algorithms or software 1

1. Applying fundamental and advanced knowledge of natural sciences as well as engineering principles to develop and design new materials and establish the relation between internal structure and physical properties using experimental, computational and theoretical tools. 3

2. Merging the existing knowledge on physical properties, design limits and fabrication methods in materials selection for a particular application or to resolve material performance related problems. 3

3. Predicting and understanding the behavior of a material under use in a specific environment knowing the internal structure or vice versa. 3

1. Familiarity with concepts in statistics and optimization, knowledge in basic differential and integral calculus, linear algebra, differential equations, complex variables, multi-variable calculus, as well as physics and computer science, and ability to use this knowledge in modeling, design and analysis of complex dynamical systems containing hardware and software components. 1

2. Ability to work in design, implementation and integration of engineering applications, such as electronic, mechanical, electromechanical, control and computer systems that contain software and hardware components, including sensors, actuators and controllers. 1


  Percentage (%)
Final 40
Midterm 30
Other 30



Molecular Biology of the Cell
Alberts, B. et al (2015) Garland

Optional Readings

Essential Cell Biology
Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P.
Garland Publishing Inc. (2014)

-Physical Biology of the Cell
Phillips, R., Kondev, J. and Theriot, J. (2009)
Garland Science ISBN 978-0-8153-4163-5.