Biochemistry II (BIO 322)

2023 Spring
Faculty of Engineering and Natural Sciences
6/5 ECTS (for students admitted in the 2013-14 Academic Year or following years)
Hüveyda Başağa,
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Emphasis is placed on the energy production and utilisation in biochemical systems so that an understanding of dynamics and energetics of biochemical systems can be achieved. Topics will also include control mechanisms in metabolism.


- Classroom sessions of this module aims to teach fundamental concepts in biochemistry including topics on Bioenergetic Principles, Carbohydrate Metabolism, TCA cycle, Electron Transport Chain, Amino Acid Metabolism, Lipid Metabolism, Biosynthetic Reactions and Integration and Function of Metabolism.
- As a co-requisite the classrooms sessions, recitation sessions of this module (BIO322R) aims to review and complement the major in-class covered concepts weekly.

After completing the in-class teaching and laboratory activities associated with this module you should be able to: (Look Learning Outcomes items)
Module-specific skills 1-5
Discipline-specific skills 6-9
Individual and key skills 10-11


  • Identify the fundamental concepts of in energy production and its utilization in biochemical systems.
  • Achieve an understanding of dynamics and energetics of biochemical systems.
  • Describe the structure and biological function of the intermediates in carbohydrate metabolism, TCA cycle and electron transport chain.
  • Describe the basic aspects of protein, membrane and lipid metabolism.
  • Describe the basic aspects integration and regulation of the carbohydrate, protein and lipid metabolism.
  • Develop a general understanding to approach essential facts and theories of energy production and its utilization in biochemical systems.
  • Identify the key features of carbohydrates, protein and lipid metabolism and differentiate these features in frame of dynamics and energetic of biochemical systems.
  • Evaluate the main aspects of the biochemistry with reference to the textbook. (Lehninger. Principles of Biochemistry, Fifth Edition, D. Nelson and M. Cox, Freeman, 2009)
  • Express basic concepts on biochemical energy production effectively by written means in home works, quizzes, examinations.
  • With some guidance, identify the covered concepts in the text book and study autonomously.
  • With some guidance, collect specific information about biochemically important molecules from the text book.


1. Understand the world, their country, their society, as well as themselves and have awareness of ethical problems, social rights, values and responsibility to the self and to others. 5

2. Understand different disciplines from natural and social sciences to mathematics and art, and develop interdisciplinary approaches in thinking and practice. 5

3. Think critically, follow innovations and developments in science and technology, demonstrate personal and organizational entrepreneurship and engage in life-long learning in various subjects; have the ability to continue to educate him/herself. 5

4. Communicate effectively in Turkish and English by oral, written, graphical and technological means. 5

5. Take individual and team responsibility, function effectively and respectively as an individual and a member or a leader of a team; and have the skills to work effectively in multi-disciplinary teams. 5

1. Possess sufficient knowledge of mathematics, science and program-specific engineering topics; use theoretical and applied knowledge of these areas in complex engineering problems. 3

2. Identify, define, formulate and solve complex engineering problems; choose and apply suitable analysis and modeling methods for this purpose. 4

3. Develop, choose and use modern techniques and tools that are needed for analysis and solution of complex problems faced in engineering applications; possess knowledge of standards used in engineering applications; use information technologies effectively. 4

4. Have the ability to design a complex system, process, instrument or a product under realistic constraints and conditions, with the goal of fulfilling specified needs; apply modern design techniques for this purpose. 3

5. Design and conduct experiments, collect data, analyze and interpret the results to investigate complex engineering problems or program-specific research areas. 4

6. Possess knowledge of business practices such as project management, risk management and change management; awareness on innovation; knowledge of sustainable development. 3

7. Possess knowledge of impact of engineering solutions in a global, economic, environmental, health and societal context; knowledge of contemporary issues; awareness on legal outcomes of engineering solutions; knowledge of behavior according to ethical principles, understanding of professional and ethical responsibility. 4

8. Have the ability to write effective reports and comprehend written reports, prepare design and production reports, make effective presentations, and give and receive clear and intelligible instructions. 3

1. Comprehend key concepts in biology and physiology, with emphasis on molecular genetics, biochemistry and molecular and cell biology as well as advanced mathematics and statistics. 5

2. Develop conceptual background for interfacing of biology with engineering for a professional awareness of contemporary biological research questions and the experimental and theoretical methods used to address them. 5

1. Use mathematics (including derivative and integral calculations, probability and statistics, differential equations, linear algebra, complex variables and discrete mathematics), basic sciences, computer and programming, and electronics engineering knowledge to (a) Design and analyze complex electronic circuits, instruments, software and electronics systems with hardware/software or (b) Design and analyze communication networks and systems, signal processing algorithms or software 2

1. Applying fundamental and advanced knowledge of natural sciences as well as engineering principles to develop and design new materials and establish the relation between internal structure and physical properties using experimental, computational and theoretical tools. 4

2. Merging the existing knowledge on physical properties, design limits and fabrication methods in materials selection for a particular application or to resolve material performance related problems. 2

3. Predicting and understanding the behavior of a material under use in a specific environment knowing the internal structure or vice versa. 2


  Percentage (%)
Final 40
Midterm 50
Homework 10



Lehninger, Principles of biochemistry