Introduction to biomaterials science and biocompatibility. Structure and properties of tissues and cells. Surface properties of materials and characterization of biomaterials surfaces. Classes of materials used in medicine: Metals, polymers, hydrogels, bioresorbable materials, ceramics, glasses, composites, thin films, fabrics and biologically functional materials. Microscopic and macroscopic structure of tissue. Mechanical properties of tissue. Pathobiological responses to implants. Medical implant design and function. Application of materials in medicine and dentistry. Cardiovascular applications. Dental implants. Orthopaedic applications. Ophthalmologic applications. Sutures. Adhesives and sealants. Tissue engineering.
Biomaterials Science and Biocompatibility (MAT 416)
2021 Spring
Faculty of Engineering and Natural Sciences
Materials Sci.& Nano Eng.(MAT)
3
6.00 / 5.00 ECTS (for students admitted in the 2013-14 Academic Year or following years)
Gözde İnce gozdeince@sabanciuniv.edu,
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English
Undergraduate
--
Formal lecture,Interactive lecture
Discussion based learning,Project based learning,Task based learning
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| Programs\Type | Required | Core Elective | Area Elective |
| BA- Political Science | |||
| BA-Cultural Studies | |||
| BA-Cultural Studies | |||
| BA-Economics | |||
| BA-Economics | |||
| BA-International Studies | |||
| BA-International Studies | |||
| BA-Management | |||
| BA-Management | |||
| BA-Political Sci.&Inter.Relat. | |||
| BA-Political Sci.&Inter.Relat. | |||
| BA-Social & Political Sciences | |||
| BA-Visual Arts&Visual Com.Des. | |||
| BA-Visual Arts&Visual Com.Des. | |||
| BS-Biological Sci.&Bioeng. | * | ||
| BS-Computer Science & Eng. | |||
| BS-Computer Science & Eng. | |||
| BS-Electronics Engineering | |||
| BS-Electronics Engineering | |||
| BS-Industrial Engineering | |||
| BS-Manufacturing Systems Eng. | |||
| BS-Materials Sci. & Nano Eng. | * | ||
| BS-Materials Science & Eng. | * | ||
| BS-Mechatronics | |||
| BS-Mechatronics | |||
| BS-Microelectronics | |||
| BS-Molecular Bio.Gen.&Bioeng | * | ||
| BS-Telecommunications | * |
CONTENT
OBJECTIVE
To understand the basic principles of biology and materials design (ceramics, polymers, metals, composites thereof), processing, testing, and characterization as is pertains to the immune response, foreign body reaction, healing versus infection & tissue engineering.
LEARNING OUTCOME
Upon successful completion of Biomaterials and Biocompatibility (MAT416), students are expected to:
- Describe the principle types, structure, testing and properties of biomaterials,
- Discuss the interplay between biomaterials and the body at various stages following contact/implantation,
- Compare a normal implant healing process against adverse scenarios such as an allergic foreign body reaction,
- List the preservation techniques of biomaterials
- Discuss the potential of tissue engineering and the potential influence of physico-chemical-mechanical actuation on the state of an implanted scaffold
Update Date:
ASSESSMENT METHODS and CRITERIA
| Percentage (%) | |
| Final | 40 |
| Midterm | 30 |
| Group Project | 30 |
RECOMENDED or REQUIRED READINGS
| Readings |
There are at least 30 excellent books related to biomaterials, biocompatibility, and tissue engineering, as well as an arsenal of journal references and Internet sources. Examples: Advances in Biomaterials, S.M. Lee (Ed.), Technomic, Lancaster, PA, 1987. Journals Internet |