Immunology (BIO 502)

2021 Fall
Faculty of Engineering and Natural Sciences
Mol.Bio.Genetic&Bioengin.(BIO)
3
10.00
Tunç Akkoç -tunc.akkoc@sabanciuniv.edu,
English
Doctoral, Master
--
Formal lecture
Interactive,Discussion based learning
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CONTENT

This is an introductory course which surveys most areas of immunology. Immunology is the study of how higher organisms deal with infectious agents. The course is designed to provide a basic understanding of molecular mechanisms underlying the development of the immune response. Topics will include molecular mechanisms of innate immunity, the structure of antibodies and T cell receptors, antigen- antibody interactions, the major histocompatibility complex, antigen presentation, generation of antibody diversity, signaling through immune system receptors, the molecular basis of immune attack, immunological tolerance, and immune memory. There will be topics from medical or bench-side immunology in last few weeks, depends on the conditions and time availability.

OBJECTIVE

To teach the history and modern molecular, cellular and organismal concepts of immunology so that each student can begin to think like an immunologist.

LEARNING OUTCOME

Understand the evolutionary principles controlling the development and function of the immune system,

Know the identity of different types of immune system cells, their functions and interactions
Understand the molecular biological mechanisms controlling antibody generation, the mechanisms of somatic VDJ recombination and somatic hypermutation,
Differentiate between the function of the antibody isotypes produced by the mammalian immune system and the significance of the major histocompatibility complex,
Detail the signal transduction events that govern cellular communication in the immune system,
Understand the methods used in immunological research.

ASSESSMENT METHODS and CRITERIA

  Percentage (%)
Final 40
Midterm 40
Assignment 10
Participation 10

RECOMENDED or REQUIRED READINGS

Textbook

Janeway's Immunobiology
Edition: 8th Author(s):Kenneth Murphy ISBN: 9780815342434