Genetics (BIO 303)

2020 Fall
Faculty of Engineering and Natural Sciences
Mol.Bio.Genetic&Bioengin.(BIO)
4
6.00 / 7.00 ECTS (for students admitted in the 2013-14 Academic Year or following years)
Christopher Mayack cmayack@sabanciuniv.edu,
Click here to view.
English
Undergraduate
NS201
Formal lecture,Interactive lecture,Seminar,Recitation,Laboratory
Interactive,Learner centered,Communicative,Discussion based learning,Project based learning,Task based learning,Guided discovery
Click here to view.

CONTENT

Aims to illustrate the basic principles of molecular and evolutionary genetics from Mendel to modern molecular biology. Examples will be chosen from prokaryotic and eukaryotic organisms and topics include: principles of heredity and variation and their application to evolution and development, phsicochemical nature of the gene, problems of recombination and gene action, selection.

OBJECTIVE

To teach fundamentals of traditional and modern concepts genetics.

LEARNING OUTCOME

Upon successful completion of this course, students should be able to:
Identify the concepts of heredity, the chemical nature of the hereditary material, and its action.
Describe the rewarding uses of genetics in their other subjects, e.g., biology, medicine.
Interpret genetic information, such as popular news reports, management decisions faced by your company, and personal health choices of you or your family.

PROGRAMME OUTCOMES


1. Understand the world, their country, their society, as well as themselves and have awareness of ethical problems, social rights, values and responsibility to the self and to others. 4

2. Understand different disciplines from natural and social sciences to mathematics and art, and develop interdisciplinary approaches in thinking and practice. 2

3. Think critically, follow innovations and developments in science and technology, demonstrate personal and organizational entrepreneurship and engage in life-long learning in various subjects. 4

4. Communicate effectively in Turkish and English by oral, written, graphical and technological means. 4

5. Take individual and team responsibility, function effectively and respectively as an individual and a member or a leader of a team; and have the skills to work effectively in multi-disciplinary teams. 4


1. Possess sufficient knowledge of mathematics, science and program-specific engineering topics; use theoretical and applied knowledge of these areas in complex engineering problems. 5

2. Identify, define, formulate and solve complex engineering problems; choose and apply suitable analysis and modeling methods for this purpose. 4

3. Develop, choose and use modern techniques and tools that are needed for analysis and solution of complex problems faced in engineering applications; possess knowledge of standards used in engineering applications; use information technologies effectively. 4

4. Ability to design a complex system, process, instrument or a product under realistic constraints and conditions, with the goal of fulfilling specified needs; apply modern design techniques for this purpose. 3

5. Design and conduct experiments, collect data, analyze and interpret the results to investigate complex engineering problems or program-specific research areas. 4

6. Knowledge of business practices such as project management, risk management and change management; awareness on innovation; knowledge of sustainable development. 2

7. Knowledge of impact of engineering solutions in a global, economic, environmental, health and societal context; knowledge of contemporary issues; awareness on legal outcomes of engineering solutions; understanding of professional and ethical responsibility. 3


1. Comprehend key concepts in biology and physiology, with emphasis on molecular genetics, biochemistry and molecular and cell biology as well as advanced mathematics and statistics. 5

2. Develop conceptual background for interfacing of biology with engineering for a professional awareness of contemporary biological research questions and the experimental and theoretical methods used to address them. 5


1. Applying fundamental and advanced knowledge of natural sciences as well as engineering principles to develop and design new materials and establish the relation between internal structure and physical properties using experimental, computational and theoretical tools. 4

2. Merging the existing knowledge on physical properties, design limits and fabrication methods in materials selection for a particular application or to resolve material performance related problems. 3

3. Predicting and understanding the behavior of a material under use in a specific environment knowing the internal structure or vice versa. 4


1. Familiarity with concepts in statistics and optimization, knowledge in basic differential and integral calculus, linear algebra, differential equations, complex variables, multi-variable calculus, as well as physics and computer science, and ability to use this knowledge in modeling, design and analysis of complex dynamical systems containing hardware and software components. 2

2. Ability to work in design, implementation and integration of engineering applications, such as electronic, mechanical, electromechanical, control and computer systems that contain software and hardware components, including sensors, actuators and controllers. 1


1. Use mathematics (including derivative and integral calculations, probability and statistics, differential equations, linear algebra, complex variables and discrete mathematics), basic sciences, computer and programming, and electronics engineering knowledge to (a) Design and analyze complex electronic circuits, instruments, software and electronics systems with hardware/software. or (b) Design and analyze communication networks and systems, signal processing algorithms or software

ASSESSMENT METHODS and CRITERIA

  Percentage (%)
Final 15.2
Midterm 30.5
Exam 7.7
Term-Paper 15.2
Case Study 6.3
Participation 1.7
Group Project 3.9
Written Report 7.8
Presentation 3.9
Homework 7.8

RECOMENDED or REQUIRED READINGS

Textbook

Daniel L. Hartl, Essential Genetics: a genomics perspective, Jones and Bartlett Learning

Readings

Recommended Readings:

The Gene by Siddhartha Mukherjee

The Violinist's Thumb by a New York Times bestselling author Sam Kean

Journal article readings (mandatory):

CRISPR: gene editing is just the beginning

Design and synthesis of a minimal bacterial genome

Genetic variation in aggregation behaviour and interacting phenotypes in Drosophila

PITX3 genotype and risk of dementia in Parkinson's disease: A population based study