Chromosome Biology (BIO 570)

2014 Spring
Faculty of Engineering and Natural Sciences
Mol.Bio.Genetic&Bioengin.(BIO)
3
10
Hikmet Budak budak@sabanciuniv.edu,
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English
Doctoral, Master
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Programs\Type Required Core Elective Area Elective
Computer Science and Engineering - With Bachelor's Degree *
Computer Science and Engineering - With Master's Degree *
Computer Science and Engineering - With Thesis *
Cyber Security - With Bachelor's Degree *
Cyber Security - With Master's Degree *
Cyber Security - With Thesis *
Electronics Engineering and Computer Science - With Bachelor's Degree *
Electronics Engineering and Computer Science - With Master's Degree *
Electronics Engineering and Computer Science - With Thesis *
Electronics Engineering - With Bachelor's Degree *
Electronics Engineering - With Master's Degree *
Electronics Engineering - With Thesis *
Energy Technologies and Management-With Thesis *
Industrial Engineering - With Bachelor's Degree *
Industrial Engineering - With Master's Degree *
Industrial Engineering - With Thesis *
Leaders for Industry Biological Sciences and Bioengineering - Non Thesis *
Leaders for Industry Computer Science and Engineering - Non Thesis *
Leaders for Industry Electronics Engineering and Computer Science - Non Thesis *
Leaders for Industry Electronics Engineering - Non Thesis *
Leaders for Industry Industrial Engineering - Non Thesis *
Leaders for Industry Materials Science and Engineering - Non Thesis *
Leaders for Industry Mechatronics Engineering - Non Thesis *
Manufacturing Engineering - Non Thesis *
Manufacturing Engineering - With Bachelor's Degree *
Manufacturing Engineering - With Master's Degree *
Manufacturing Engineering - With Thesis *
Materials Science and Nano Engineering-(Pre:Materials Science and Engineering) *
Materials Science and Nano Engineering-(Pre:Materials Science and Engineering) *
Materials Science and Nano Engineering - With Thesis (Pre.Name: Materials Science and Engineering) *
Mechatronics Engineering - With Bachelor's Degree *
Mechatronics Engineering - With Master's Degree *
Mechatronics Engineering - With Thesis *
Molecular Biology, Genetics and Bioengineering (Prev. Name: Biological Sciences and Bioengineering) *
Molecular Biology, Genetics and Bioengineering-(Prev. Name: Biological Sciences and Bioengineering) *
Molecular Biology,Genetics and Bioengineering-With Thesis (Pre.Name:Biological Sciences and Bioeng.) *
Physics - Non Thesis *
Physics - With Bachelor's Degree
Physics - With Master's Degree

CONTENT

This course deals with major concepts in exploration of the relationships between chromosome structure, function and behaviour. Topics include; basic properties of chromosomes, specialized chromosomes (polytene chromosomes, lampbrush chromosomes) chromatin and higher-order structure of chromosomes, bacterial and eukaryotic chromosomes, centromeres, dynamic behaviour of telomeres, genome organization and function, control of mitotic and meiotic segregation, chromosome aberrations, transposons, chromosome purification, chromosome banding, in situ hybridization, chromosome polyploidy, aneuploidy and haploidy. Necessary equipment and facilities of the molecular cytogenetics laboratory, microscopy, analysis of signal and imaging will be also covered.

LEARNING OUTCOMES

  • After completing this course, students should be able to accomplish the following outcomes: Chromosome structure and function in diverse organisms (Halving the Chromosome Number, Contrast haploid and diploid chromosome numbers, Explain what is meant by homologous chromosomes., Genetic Variation) The role of crossing-over in chromosomes List some human syndromes and plant diseases that are associated with changes in chromosome