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Code BIO 321
Term 201701
Title Biochemistry I
Faculty Faculty of Engineering and Natural Sciences
Subject Mol.Bio.Genetic&Bioengin.(BIO)
SU Credit 4
ECTS Credit 8.00 / 7.00 ECTS (for students admitted in the 2013-14 Academic Year or following years)
Instructor(s) Huveyda Basa?a huveyda@sabanciuniv.edu,
Detailed Syllabus
Language of Instruction English
Level of Course Undergraduate
Type of Course Click here to view.
Prerequisites
(only for SU students)
NS102 MATH101
Mode of Delivery Formal lecture,Interactive lecture,On-line task/distance,Recitation,One-to-one tutorial,Laboratory
Planned Learning Activities Interactive,Learner centered,Communicative,Discussion based learning,Project based learning,Task based learning,Guided discovery
Content

Chemical nature of cellular components; enzymes and mechanism of enzyme activity; energy interconversions and biosynthetic reactions, including template dependent reactions, and some aspects of control mechanisms. Weekly laboratory session introduces the major experimental tools used in modern biology. Also part of the "core course" pools for the BIO, MAT degree programs.

Objective

AIMS
- Classroom sessions of this module aims to teach fundamental concepts in biochemistry including topics on Amino Acids, Protein Structure & Function, Enzyme Kinetics, Carbohydrates, Nucleotides and Lipids to the students who do have at least D ?grade in freshman level Biology, Chemistry (NS 102 ? Science of Nature II) and Calculus (MATH 101 & MATH 102) courses.
- As a co-requisite the classrooms sessions, laboratory sessions of this module (BIO321L) aims to introduce major experimental methods used in modern biochemistry weekly by simultaneously complementing the in-class covered concepts.

INTENDED LEARNING OUTCOMES
After completing the in-class teaching and laboratory activities associated with this module you should be able to: (Look Learning Outcomes items)
Module-specific skills 1-5
Discipline-specific skills 6-9
Individual and key skills 10-12

Learning Outcome

Identify the fundamental concepts of biochemistry
Describe the structures and functions of amino acids.
Describe the structure and biological function relationship of proteins.
Describe the basic aspects of Michelis-Menten enzyme kinetics and catalysis.
Describe the main aspects of the structures and functions of carbohydrates, nucleotides and lipids.
Develop a general understanding to approach essential facts and theories of biochemistry.
Identify the key features of amino acids, proteins, enzymes, carbohydrates, nucleotides and lipids and use these features in frame of a biochemical experimental design and method in a laboratory context, with some guidance.
With some guidance, analyze, interpret and report biochemically derived data, which have lowered level of complexity than the ones gained from real world experimentations, in details.
Evaluate the main aspects of the biochemistry with reference to the textbook. (Lehninger. Principles of Biochemistry, Fifth Edition, D. Nelson and M. Cox, Freeman, 2009)
Express basic biochemical concepts effectively by written means in homeworks, quizzes, examinations and lab notebooks.
With some guidance, identify the covered concepts in the text book and study autonomously.
With some guidance, collect specific information about biochemically important molecules from the text book and understand their roles in a biochemical laboratory method.

Programme Outcomes
 
Common Outcomes For All Programs
1 Understand the world, their country, their society, as well as themselves and have awareness of ethical problems, social rights, values and responsibility to the self and to others. 5
2 Understand different disciplines from natural and social sciences to mathematics and art, and develop interdisciplinary approaches in thinking and practice. 5
3 Think critically, follow innovations and developments in science and technology, demonstrate personal and organizational entrepreneurship and engage in life-long learning in various subjects. 5
4 Communicate effectively in Turkish and English by oral, written, graphical and technological means. 5
5 Take individual and team responsibility, function effectively and respectively as an individual and a member or a leader of a team; and have the skills to work effectively in multi-disciplinary teams. 5
Common Outcomes ForFaculty of Eng. & Natural Sci.
1 Possess sufficient knowledge of mathematics, science and program-specific engineering topics; use theoretical and applied knowledge of these areas in complex engineering problems. 5
2 Identify, define, formulate and solve complex engineering problems; choose and apply suitable analysis and modeling methods for this purpose. 3
3 Develop, choose and use modern techniques and tools that are needed for analysis and solution of complex problems faced in engineering applications; possess knowledge of standards used in engineering applications; use information technologies effectively. 4
4 Ability to design a complex system, process, instrument or a product under realistic constraints and conditions, with the goal of fulfilling specified needs; apply modern design techniques for this purpose. 3
5 Design and conduct experiments, collect data, analyze and interpret the results to investigate complex engineering problems or program-specific research areas. 5
6 Knowledge of business practices such as project management, risk management and change management; awareness on innovation; knowledge of sustainable development. 3
7 Knowledge of impact of engineering solutions in a global, economic, environmental, health and societal context; knowledge of contemporary issues; awareness on legal outcomes of engineering solutions; understanding of professional and ethical responsibility. 5
Molecular Biology, Genetics and Bioengineering Program Outcomes Required Courses
1 Comprehend key concepts in biology and physiology, with emphasis on molecular genetics, biochemistry and molecular and cell biology as well as advanced mathematics and statistics. 5
2 Develop conceptual background for interfacing of biology with engineering for a professional awareness of contemporary biological research questions and the experimental and theoretical methods used to address them. 5
Materials Science and Nano Engineering Program Outcomes Core Electives
1 Applying fundamental and advanced knowledge of natural sciences as well as engineering principles to develop and design new materials and establish the relation between internal structure and physical properties using experimental, computational and theoretical tools. 3
2 Merging the existing knowledge on physical properties, design limits and fabrication methods in materials selection for a particular application or to resolve material performance related problems. 3
3 Predicting and understanding the behavior of a material under use in a specific environment knowing the internal structure or vice versa. 3
Electronics Engineering Program Outcomes Area Electives
1 Use mathematics (including derivative and integral calculations, probability and statistics), basic sciences, computer and programming, and electronics engineering knowledge to design and analyze complex electronic circuits, instruments, software and electronics systems with hardware/software. 3
2 Analyze and design communication networks and systems, signal processing algorithms or software using advanced knowledge on differential equations, linear algebra, complex variables and discrete mathematics. 3
Assessment Methods and Criteria
  Percentage (%)
Final 30
Midterm 40
Group Project 20
Homework 10
Recommended or Required Reading
Textbook

Biochemistry, The Molecular Basis of Life
Trudy McKee, James McKee
Mc Graw Hill

Readings

from various sources